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Invitrogen™ POLH Recombinant Rabbit Monoclonal Antibody (1Y6C10)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA557933

Encompass_Preferred

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Catalog No. MA557933


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Description

Description

Immunogen sequence: KNGSWLYAMC RGIEHDPVKP RQLPKTIGCS KNFPGKTALA TREQVQWWLL QLAQELEERL TKDRNDNDRV ATQLVVSIRV QGDKRLSSLR RCCALTRYDA HKMSHDAFTV IKNCNTSGIQ TEWSPPLTML FLCATKFSAS APSSSTDITS FLS.

The XPA gene encodes a zinc metalloprotein that preferentially binds to DNA damaged by UV radiation and chemical carcinogens and is required for the incision step during nucleotide excision repair The XPB and XPD genes encode DNA helicases involved in several DNA metabolic pathways, including DNA repair and transcription, and the XPG gene product is an endonuclease that cuts on the 3' side of a DNA lesion during nucleotide excision repair. Molecular defects in the XP variant (POL H) group maintain normal excision repair, yet they result in a substantial reduction in the ability to synthesize intact daughter DNA strands during DNA replication following DNA damage.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

POLH
Recombinant Monoclonal
1.1 mg/mL
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Q9Y253
POLH
Recombinant fusion protein containing a sequence corresponding to amino acids 293-445 of human DNA polymerase eta (NP_006493.1).
20 μL
Primary
Human
Antibody
IgG
ELISA, Western Blot
1Y6C10
Unconjugated
POLH
DNA polymerase eta; DNA-directed DNA polymerase eta; FLJ16395; FLJ21978; Polh; polymerase (DNA directed), eta; polymerase (DNA directed), eta (RAD 30 related); polymerase (DNA) eta; RAD30; RAD30 homolog A; RAD30A; Xeroderma pigmentosum variant type protein; xeroderma pigmentosum variant type protein homolog; XP V; XPV; XP-V
Rabbit
Protein A
RUO
5429
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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