Learn More
Invitrogen™ POLH Recombinant Rabbit Monoclonal Antibody (1Y6C10)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA557933

Description
Immunogen sequence: KNGSWLYAMC RGIEHDPVKP RQLPKTIGCS KNFPGKTALA TREQVQWWLL QLAQELEERL TKDRNDNDRV ATQLVVSIRV QGDKRLSSLR RCCALTRYDA HKMSHDAFTV IKNCNTSGIQ TEWSPPLTML FLCATKFSAS APSSSTDITS FLS.
The XPA gene encodes a zinc metalloprotein that preferentially binds to DNA damaged by UV radiation and chemical carcinogens and is required for the incision step during nucleotide excision repair The XPB and XPD genes encode DNA helicases involved in several DNA metabolic pathways, including DNA repair and transcription, and the XPG gene product is an endonuclease that cuts on the 3' side of a DNA lesion during nucleotide excision repair. Molecular defects in the XP variant (POL H) group maintain normal excision repair, yet they result in a substantial reduction in the ability to synthesize intact daughter DNA strands during DNA replication following DNA damage.
Specifications
POLH | |
Recombinant Monoclonal | |
1.1 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
Q9Y253 | |
POLH | |
Recombinant fusion protein containing a sequence corresponding to amino acids 293-445 of human DNA polymerase eta (NP_006493.1). | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |
ELISA, Western Blot | |
1Y6C10 | |
Unconjugated | |
POLH | |
DNA polymerase eta; DNA-directed DNA polymerase eta; FLJ16395; FLJ21978; Polh; polymerase (DNA directed), eta; polymerase (DNA directed), eta (RAD 30 related); polymerase (DNA) eta; RAD30; RAD30 homolog A; RAD30A; Xeroderma pigmentosum variant type protein; xeroderma pigmentosum variant type protein homolog; XP V; XPV; XP-V | |
Rabbit | |
Protein A | |
RUO | |
5429 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.