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POLI Mouse anti-Human, Clone: OTI1C8, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF801478

Catalog No. 50-166-5609


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5 ft.-deoxyribose phosphate at abasic sites, but may not have lyase activity.
Specifications

Specifications

POLI
Monoclonal
Unconjugated
POLI
Lyophilized
POLI
Human recombit protein fragment corresponding to amino acids 458-740 of human POLI produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
OTI1C8
PBS with 8% trehalose and no preservative; pH 7.3
Q9UNA4
RAD30B, RAD3OB, eta2
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11201
SDS
Documents
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