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POLI Mouse anti-Human, Clone: OTI1C8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF801478

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5′-deoxyribose phosphate at abasic sites, but may not have lyase activity.Specifications
POLI | |
Monoclonal | |
Unconjugated | |
POLI | |
RAD30B, RAD3OB, eta2 | |
Mouse | |
Affinity Chromatography | |
RUO | |
11201 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI1C8 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9UNA4 | |
POLI | |
Human recombit protein fragment corresponding to amino acids 458-740 of human POLI produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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