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Invitrogen™ POLK Polyclonal Antibody
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Catalog No. PIPA584774
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100 μL
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PIPA584774 100 μL
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Catalog No. PIPA584774 Supplier Invitrogen™ Supplier No. PA584774
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDSTKEKCDS YKDDLLLRMG LNDNKAGMEG LDKEKINKII MEATKGSRFY GNELKKEKQV NQRIENMMQQ KAQITSQQL Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 95%.

External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLK
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POLK
Gene Accession No. Q9UBT6
Gene Alias DinB homolog 1; DINB protein; Dinb1; DINP; DNA damage-inducible protein b; DNA polymerase kappa; DNA-directed DNA polymerase kappa; LOW QUALITY PROTEIN: DNA polymerase kappa; POLK; POLQ; polymerase (DNA directed) kappa; polymerase (DNA directed), kappa; polymerase (DNA) kappa
Gene Symbols POLK
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human POLK. Recombinant protein control fragment (Product #RP-107622).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51426
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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