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Invitrogen™ POLK Polyclonal Antibody
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Catalog No. PIPA588323
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100 μL
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PIPA588323 100 μL
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Catalog No. PIPA588323 Supplier Invitrogen™ Supplier No. PA588323
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDSTKEKCDS YKDDLLLRMG LNDNKAGMEG LDKEKINKII MEATKGSRFY GNELKKEKQV NQRIENMMQQ KAQITSQQLR KAQLQVDRFA MELEQSRNLS; Positive Samples: 22RV1, SKOV3, U-87MG, Mouse liver; Cellular Location: Nucleus.

External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLK
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene POLK
Gene Accession No. Q9QUG2, Q9UBT6
Gene Alias DinB homolog 1; DINB protein; Dinb1; DINP; DNA damage-inducible protein b; DNA polymerase kappa; DNA-directed DNA polymerase kappa; LOW QUALITY PROTEIN: DNA polymerase kappa; POLK; POLQ; polymerase (DNA directed) kappa; polymerase (DNA directed), kappa; polymerase (DNA) kappa
Gene Symbols POLK
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27015, 51426
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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