Invitrogen™ POLR2E Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530123

Catalog No. PIPA530123

Description

Recommended positive controls: A549. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (97%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.

Specifications

• Antigen: POLR2E
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR2E
• Gene Alias: 2410021N14Rik; 25kDa; AW208866; DNA directed RNA polymerase II 23 kda polypeptide; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; DNA-directed RNA polymerase subunit RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1; hRPB25; hsRPB5; Polr2e; polymerase (RNA) II (DNA directed) polypeptide E; polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; polymerase (RNA) II subunit E; RNA polymerase II subunit E; RNA polymerase II, I and III subunit E; RNA polymerases I, II, and III subunit ABC1; RPABC1; RPB5; RPB5 homolog; XAP4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5434
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.49 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P19388
• Gene Symbols: POLR2E
• Immunogen: Recombinant fragment corresponding to a region within amino acids 22 and 210 of Human RNA polymerase IIE.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov