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Invitrogen™ POLR2E Polyclonal Antibody
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Catalog No. PIPA595916
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100 μL
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PIPA595916 100 μL
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Catalog No. PIPA595916 Supplier Invitrogen™ Supplier No. PA595916
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDDEEETYRL WKIRKTIMQL CHDRGYLVTQ DELDQTLEEF KAQFGDKPSE GRPRRTDLTV LVAHNDDPTD QMFVFFPEEP KVGIKTIKVY CQRMQEENIT RALIVVQQGM TPSAKQSLVD MAPKYILEQF LQQELLINIT EHELVPEHVV MTKEEVTELL ARYKLRENQL PRIQAGDPVA RYFGIKRGQV VKIIRPSETA GRYITYRLVQ; Positive Samples: HepG2, U-937, SW620, Raji, Jurkat, SKOV3; Cellular Location: Nucleus.

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLR2E
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.76 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene POLR2E
Gene Accession No. P19388
Gene Alias 2410021N14Rik; 25kDa; AW208866; DNA directed RNA polymerase II 23 kda polypeptide; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; DNA-directed RNA polymerase subunit RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1; hRPB25; hsRPB5; Polr2e; polymerase (RNA) II (DNA directed) polypeptide E; polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; polymerase (RNA) II subunit E; RNA polymerase II subunit E; RNA polymerase II, I and III subunit E; RNA polymerases I, II, and III subunit ABC1; RPABC1; RPB5; RPB5 homolog; XAP4
Gene Symbols POLR2E
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POLR2E (NP_0026862).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5434
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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