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Invitrogen™ POLR2I Polyclonal Antibody
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Catalog No. PIPA560938
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100 μL
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PIPA560938 100 μL
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Catalog No. PIPA560938 Supplier Invitrogen™ Supplier No. PA560938
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PDGTYEPGFV GIRFCQECNN MLYPKEDKEN RILLYACRNC DYQQEADNSC IYVNKITHEV DELTQIIADV SQDPTLPRTE DHPCQKCGHK EAVFFQSHSA Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

POLR2I is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. POLR2I has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLR2I
Applications ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POLR2I
Gene Accession No. P36954, P60898
Gene Alias 2810002B19Rik; DNA-directed RNA polymerase II 14.5 kDa polypeptide; DNA-directed RNA polymerase II subunit I; DNA-directed RNA polymerase II subunit RPB9; hRPB14.5; Polr2i; polymerase (RNA) II (DNA directed) polypeptide I; polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa; polymerase (RNA) II subunit I; RNA polymerase II 14.5 kDa subunit; RNA polymerase II subunit B9; RNA polymerase II subunit I; RPB14.5; RPB9; Unknown (protein for MGC:133488); zgc:103515
Gene Symbols POLR2I
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human POLR2I. Recombinant protein control fragment (Product #RP-89316).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 292778, 5438, 69920
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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