Invitrogen™ POLR2I Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565152

Catalog No. PIPA565152

Description

Immunogen sequence: DELTQIIADVS QDPTLPRTED HPCQKCGHKE AVFFQSHSAR AEDAMRLYYV CT Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

POLR2I is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. POLR2I has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.

Specifications

• Antigen: POLR2I
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR2I
• Gene Alias: 2810002B19Rik; DNA-directed RNA polymerase II 14.5 kDa polypeptide; DNA-directed RNA polymerase II subunit I; DNA-directed RNA polymerase II subunit RPB9; hRPB14.5; Polr2i; polymerase (RNA) II (DNA directed) polypeptide I; polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa; polymerase (RNA) II subunit I; RNA polymerase II 14.5 kDa subunit; RNA polymerase II subunit B9; RNA polymerase II subunit I; RPB14.5; RPB9; Unknown (protein for MGC:133488); zgc:103515
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5438
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P36954
• Gene Symbols: POLR2I
• Immunogen: Recombinant Human POLR2I. Recombinant protein control fragment (Product #RP-105903).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG