Invitrogen™ POLR2K Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566564

Catalog No. PIPA566564

Description

Immunogen sequence: DVQPPKQQPMI YICGECHTEN EIKSRDPIRC RECGYRIMYK KRTKRLV Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family. The gene encoding POLR2K is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

Specifications

• Antigen: POLR2K
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR2K
• Gene Alias: ABC10-alpha; DNA directed RNA polymerases I, II, and III 7.0 kda polypeptide; DNA-directed RNA polymerase II subunit K; DNA-directed RNA polymerases I, II, and III subunit RPABC4; hRPB7.0; hsRPB10a; MafY; mCG145114-like; metallothionein-I gene transcription activator; Mt1a; POLR2K; polymerase (RNA) II (DNA directed) polypeptide K; polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa; polymerase (RNA) II subunit K; RNA polymerase II 7.0 kDa subunit; RNA polymerase II subunit K; RNA polymerases I, II, and III subunit ABC4; RPABC4; RPB10alpha; RPB12; RPB7.0
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5440
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P53803
• Gene Symbols: POLR2K
• Immunogen: Recombinant Human POLR2K. Recombinant protein control fragment (Product #RP-107219).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov