Invitrogen™ POLR3E Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118175

Catalog No. PIPA5118175

Description

POLR3E Polyclonal Antibody for Western Blot, IP

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Specifications

• Antigen: POLR3E
• Classification: Polyclonal
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: Q9NVU0
• Gene Symbols: POLR3E
• Immunogen: E. coli-derived Human POLR3E fragment.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: POLR3E
• Gene Alias: DNA-directed RNA polymerase III 80 kDa polypeptide; DNA-directed RNA polymerase III subunit RPC5; KIAA1452; POLR3E; polymerase (RNA) III (DNA directed) polypeptide E; polymerase (RNA) III (DNA directed) polypeptide E (80kD); polymerase (RNA) III subunit E; RGD1308086; RNA polymerase III 80 kDa subunit RPC5; RNA polymerase III polypeptide E; RNA polymerase III subunit 5; RNA polymerase III subunit C5; RNA polymerase III subunit E; RPC5; Sex-lethal interactor homolog; Sin; Sxl interactor
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55718
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid