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POLR3H Mouse anti-Human, Clone: OTI4D8, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF809432

Encompass_Preferred

Catalog No. 50-166-9489


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
Specifications

Specifications

POLR3H
Monoclonal
Unconjugated
POLR3H
RPC22.9, RPC8
Mouse
Affinity Chromatography
RUO
171568
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI4D8
PBS with 8% trehalose and no preservative; pH 7.3
Q9Y535
POLR3H
Full length human recombit protein of human POLR3H produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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