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Invitrogen™ POLR3H Polyclonal Antibody
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Catalog No. PIPA5101561
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PIPA5101561 100 μL
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Catalog No. PIPA5101561 Supplier Invitrogen™ Supplier No. PA5101561
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RPC8.

RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLR3H
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene POLR3H
Gene Accession No. Q9D2C6, Q9Y535
Gene Alias 5031409G22Rik; DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide; DNA-directed RNA polymerase III subunit H; DNA-directed RNA polymerase III subunit RPC8; KIAA1665; POLR3H; polymerase (RNA) III (DNA directed) polypeptide H; polymerase (RNA) III (DNA directed) polypeptide H (22.9kD); polymerase (RNA) III subunit H; RNA nucleotidyltransferase (DNA-directed); RNA polymerase III subunit 22.9 kDa subunit; RNA polymerase III subunit C7; RNA polymerase III subunit C8; RNA polymerase III subunit H; RPC22.9; RPC8
Gene Symbols POLR3H
Host Species Rabbit
Immunogen A synthesized peptide derived from human POLR3H(Accession Q9Y535), corresponding to amino acid residues V153-S203.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171568, 300088, 78929
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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