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Invitrogen™ Polymyxin B Monoclonal Antibody (45)
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Catalog No. 01676524
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Catalog No. Quantity
01-676-524 1 mL
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Catalog No. 01-676-524 Supplier Invitrogen™ Supplier No. MA140133
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Description

Mouse Monoclonal Antibody

This antibody binds to free Polymyxin B as well as to Polymyxin B already bound to LPS.

The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo. Antibodies to PMB allow for the quantitative study of interaction of PMB/LPS interactions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Polymyxin B
Applications ELISA, Western Blot
Classification Monoclonal
Clone 45
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.02% sodium azide
Gene Alias PMB
Host Species Mouse
Immunogen Polymixin B.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgM
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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