Invitrogen™ POMK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553037

Catalog No. PIPA553037

Description

Immunogen sequence: TSNFSILAND LDALPLVNHS SGMLVKCGHR ELHGDFVAPE QLWPYGEDVP FHDDLMPSYD EKIDIWKIPD ISSFLLGHIE GSDMVRFHLF DIHKACKSQT PSERPTAQDV LETYQKVLDT L Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.

Specifications

• Antigen: POMK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POMK
• Gene Alias: 4930444A02Rik; MDDGA12; MDDGC12; Pomk; probable inactive protein kinase-like protein SgK196; protein kinase-like protein SgK196; protein kinase-like protein SgK196-like; protein O-mannose kinase; protein-O-mannose kinase; RGD1310810; SGK196; sugen kinase 196
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84197
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H5K3
• Gene Symbols: POMK
• Immunogen: Recombinant protein corresponding to Human POMK. Recombinant protein control fragment (Product #RP-90559).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG