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Invitrogen™ PON1 Monoclonal Antibody (4G8D3)
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Catalog No. PIMA538605
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100 μg
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PIMA538605 100 μg
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Catalog No. PIMA538605 Supplier Invitrogen™ Supplier No. MA538605
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PON1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4G8D3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene PON1
Gene Accession No. P27169
Gene Alias 2810004E20; 6330405I24Rik; A esterase 1; A-esterase 1; A-esterase 2; AI481612; AI786302; Aromatic esterase 1; aromatic esterase 2; arylesterase 1; arylesterase 2; arylesterase 3; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESA; ESAesterase A; esterase A; K-45; MVCD5; paraoxanase-3; paraoxonase 1; paraoxonase 2; paraoxonase 3; paraoxonase B-type; paraoxonase nirs; PON; PON 1; PON 2; Pon1; PON2; PON3; serum aryldiakylphosphatase; serum aryldialkylphosphatase 1; Serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 1; Serum paraoxonase/arylesterase 2; serum paraoxonase/lactonase 3
Gene Symbols PON1
Host Species Mouse
Immunogen Purified recombinant fragment of human PON1 (aa: 20-155) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5444
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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