PON1 Monoclonal Antibody (OTI2A9), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-3652	100 μL
50-254-1425	30 μL

Catalog No. 50-167-3652 Supplier OriGene Supplier No. TA502612

Description

Mouse Monoclonal Antibody

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson′s disease.

Specifications

• Antigen: PON1
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: OTI2A9
• Concentration: 0.34 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: PON1
• Gene Accession No.: P27169
• Gene Alias: ESA, MVCD5, PON
• Gene Symbols: PON1
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human PON1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5444
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1