PON1 Mouse anti-Human, Clone: OTI2A6, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA600113

Catalog No. 50-167-7198

Description

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson′s disease.

Specifications

• Antigen: PON1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with <5% trehalose and 0.05% sodium azide
• Gene Accession No.: P27169
• Gene Symbols: PON1
• Immunogen: Full length human recombit protein of human HPGD produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: OTI2A6
• Conjugate: Unconjugated
• Gene: PON1
• Gene Alias: ESA, MVCD5, PON
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5444
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid