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Invitrogen™ PON1 Recombinant Rabbit Monoclonal Antibody (4X7X2)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA538069
Description
Positive Samples: Mouse liver, HepG2 Immunogen sequence: TGSEDLEILP NGLAFISSGL KYPGIKSFNP NSPGKILLMD LNEEDPTVLE LGITGSKFDV SSFNPHGIST FTDEDNAMYL LVVNHPDAKS TVELFKFQEE E.
The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.
Specifications
PON1 | |
Recombinant Monoclonal | |
0.27 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P27169, P52430, P55159 | |
PON1 | |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PON1 (P27169). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
4X7X2 | |
Unconjugated | |
PON1 | |
2810004E20; 6330405I24Rik; A esterase 1; A-esterase 1; A-esterase 2; AI481612; AI786302; Aromatic esterase 1; aromatic esterase 2; arylesterase 1; arylesterase 2; arylesterase 3; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESA; ESAesterase A; esterase A; K-45; MVCD5; paraoxanase-3; paraoxonase 1; paraoxonase 2; paraoxonase 3; paraoxonase B-type; paraoxonase nirs; PON; PON 1; PON 2; Pon1; PON2; PON3; serum aryldiakylphosphatase; serum aryldialkylphosphatase 1; Serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 1; Serum paraoxonase/arylesterase 2; serum paraoxonase/lactonase 3 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
18979, 5444, 84024 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
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