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PON1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986333
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50-198-6333 100 μL
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Catalog No. 50-198-6333 Supplier Bioss Supplier No. BS5107R
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Description

Rabbit Polyclonal Antibody

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson′s disease.

Specifications

Antigen PON1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PON1
Gene Accession No. P27169
Gene Alias A esterase 1; A-esterase 1; Aromatic esterase 1; arylesterase 1; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESA; ESAesterase A; esterase A; K-45; MVCD5; paraoxonase 1; paraoxonase B-type; PON; PON 1; PON1; serum aryldiakylphosphatase; Serum aryldialkylphosphatase 1; Serum paraoxonase/arylesterase 1
Gene Symbols PON1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PON1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5444
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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