Invitrogen™ PON2 Polyclonal Antibody

Catalog No.	Quantity
PIPA519257	100 μg

Catalog No. PIPA519257 Supplier Invitrogen™ Supplier No. PA519257

Description

Goat Polyclonal Antibody

This antibody is predicted to react with canine, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: PON2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: PON2
• Gene Accession No.: Q15165
• Gene Alias: 6330405I24Rik; A esterase 2; A-esterase 2; AI481612; aromatic esterase 2; arylesterase 2; paraoxonase 2; paraoxonase nirs; PON 2; PON2; Serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
• Gene Symbols: PON2
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (EKPRARELRIS) corresponding to the internal amino acids of PON2 (aa 93-104).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5445
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG