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Invitrogen™ PON2 Polyclonal Antibody
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Catalog No. PIPA5115781
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100 μL
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PIPA5115781 100 μL
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Catalog No. PIPA5115781 Supplier Invitrogen™ Supplier No. PA5115781
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PON2.

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PON2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene PON2
Gene Accession No. Q15165, Q62086, Q6AXM8
Gene Alias 6330405I24Rik; A esterase 2; A-esterase 2; AI481612; aromatic esterase 2; arylesterase 2; paraoxonase 2; paraoxonase nirs; PON 2; PON2; Serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
Gene Symbols PON2
Host Species Rabbit
Immunogen A synthesized peptide derived from human PON2(Accession Q15165), corresponding to amino acid residues K249-P299.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 296851, 330260, 5445
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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