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Invitrogen™ POU6F1 Polyclonal Antibody
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Catalog No. PIPA537884
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100 μg
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PIPA537884 100 μg
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Catalog No. PIPA537884 Supplier Invitrogen™ Supplier No. PA537884
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Goat Polyclonal Antibody

This antibody is predicted to react with rat, dog and cow based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POU6F1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene POU6F1
Gene Accession No. Q07916, Q14863
Gene Alias 2310038G18Rik; brain-5; Brain-specific homeobox/POU domain protein 5; BRN5; brn-5; brn-5 protein; C79593; cns-1; Emb; MPOU; mPOU homeobox protein; Octamer-binding transcription factor EMB; POU class 6 homeobox 1; POU domain, class 6, transcription factor 1; Pou6f1; TCFB1; transcription regulatory protein MCP-1
Gene Symbols POU6F1
Host Species Goat
Immunogen Peptide with sequence C-ETPTVSQLVSKPHTP, from the internal region of POU6F1 (aa 121-135).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19009, 5463
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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