Invitrogen™ POU6F1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA537884

Catalog No. PIPA537884

Description

This antibody is predicted to react with rat, dog and cow based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.

Specifications

• Antigen: POU6F1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POU6F1
• Gene Alias: 2310038G18Rik; brain-5; Brain-specific homeobox/POU domain protein 5; BRN5; brn-5; brn-5 protein; C79593; cns-1; Emb; MPOU; mPOU homeobox protein; Octamer-binding transcription factor EMB; POU class 6 homeobox 1; POU domain, class 6, transcription factor 1; Pou6f1; TCFB1; transcription regulatory protein MCP-1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 19009, 5463
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q07916, Q14863
• Gene Symbols: POU6F1
• Immunogen: Peptide with sequence C-ETPTVSQLVSKPHTP, from the internal region of POU6F1 (aa 121-135).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov