Invitrogen™ POU6F1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528226

Catalog No. PIPA528226

Description

Recommended positive controls: A549, H1299, HCT116. Predicted reactivity: Mouse (94%), Rat (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.

Specifications

• Antigen: POU6F1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POU6F1
• Gene Alias: 2310038G18Rik; brain-5; Brain-specific homeobox/POU domain protein 5; BRN5; brn-5; brn-5 protein; C79593; cns-1; Emb; MPOU; mPOU homeobox protein; Octamer-binding transcription factor EMB; POU class 6 homeobox 1; POU domain, class 6, transcription factor 1; Pou6f1; TCFB1; transcription regulatory protein MCP-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5463
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14863
• Gene Symbols: POU6F1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human POU6F1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG