Invitrogen™ PP1 alpha/beta/gamma Recombinant Rabbit Monoclonal Antibody (HL1677)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547138

Catalog No. PIMA547138

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription Increased PP1 activity has been observed in the end stage of heart failure Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer PP1 alpha is one of the three catalytic subunits of protein phosphatase 1 (PP1) This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity PP1 beta encodes the beta isozyme and PP1 gamma encodes the gamma isozyme.

Specifications

• Antigen: PP1 alpha/beta/gamma
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Alias: HEL-S-80p; NSLH2; PP1A; PP-1A; PP1alpha; PP1B; PP-1B; PP1beta; PP1C; PP-1G; PPP1A; PPP1CD; PPP1G; protein phosphatase 1 catalytic subunit alpha; protein phosphatase 1 catalytic subunit beta; protein phosphatase 1 catalytic subunit gamma
• Immunogen: Recombinant fragment of human PP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: HL1677
• Conjugate: Unconjugated
• Gene Accession No.: P29466, P48729, Q8N752
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 122011, 1452, 834
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid