Invitrogen™ PP1 beta Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528225

Catalog No. PIPA528225

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, PPP1CB shRNA-transfected 293T, Mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (99%), Xenopus laevis (100%), Dog (99%), Pig (100%), Rabbit (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

Specifications

• Antigen: PP1 beta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ppp1cb
• Gene Alias: 1200010B19; epididymis secretory sperm binding protein Li 80p; HEL-S-80p; hypothetical protein LOC538829; MGC21657; PP1B; PP-1B; PP1beta; PP1-BETA; PP2CB; PP2CBETA; PP2C-beta-X; PPC2BETAX; PPP1CB; PPP1CD; protein phosphatase 1; protein phosphatase 1 catalytic subunit beta; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, delta isoform; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase-1a; serine/threonine protein phosphatase PP1-beta catalytic subunit; serine/threonine-protein phosphatase PP1-beta catalytic subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19046, 25594, 5500
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.6 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P62140, P62141, P62142
• Gene Symbols: Ppp1cb
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 274 of Human PPP1CB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG