Invitrogen™ PPAN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106430

Catalog No. PIPA5106430

Description

Antibody detects endogenous levels of total PPAN.

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

Specifications

• Antigen: PPAN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPAN
• Gene Alias: A230087P06Rik; Brix domain-containing protein 3; BXDC3; homolog of S. cerevisiae SSF1; Peter Pan homolog; peter pan homolog (Drosophila); Ppan; second-step splicing factor 1; SSF; Ssf1; ssf-1; SSF2; suppressor of sterile four 1; suppressor of SWI4 1 homolog
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 235036, 298699, 56342
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q91YU8, Q9NQ55
• Gene Symbols: PPAN
• Immunogen: A synthesized peptide derived from human PPAN(Accession Q9NQ55), corresponding to amino acid residues Q408-D458.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG