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Invitrogen™ PPAPDC1A Polyclonal Antibody
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Catalog No. PIPA5116155
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400 μL
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PIPA5116155 400 μL
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Catalog No. PIPA5116155 Supplier Invitrogen™ Supplier No. PA5116155
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Rabbit Polyclonal Antibody

PPAPDC1A Polyclonal Antibody for IHC (P), Western Blot

Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPAPDC1A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PLPP4
Gene Accession No. Q0VBU9, Q5VZY2
Gene Alias C030048B12Rik; diacylglycerol pyrophosphate like 2; diacylglycerol pyrophosphate phosphatase-like 2; DPPL2; Gm1090; phosphatidate phosphatase PPAPDC1A; phosphatidic acid phosphatase type 2 domain containing 1A; phosphatidic acid phosphatase type 2 domain-containing protein 1A; Phospholipid phosphatase 4; PLPP4; PPAPDC1; Ppapdc1a; RGD1306289; RP11-257O17.1
Gene Symbols PLPP4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human PPAPDC1A.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 196051, 381925
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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