Invitrogen™ PPAPDC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520865

Catalog No. PIPA520865

Description

A suggested positive control is Raji cell lysate. PA5-20865 can be used with blocking peptide PEP-0979.

PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.

Specifications

• Antigen: PPAPDC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLPP6
• Gene Alias: 4932443D16Rik; bA6J24.6; FLJ46512; FLJ90191; MGC15483; PDP1; phosphatidic acid phosphatase type 2 domain containing 2; phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; PLPP6; polyisoprenoid diphosphate phosphatase type 1; PPAP2 domain-containing protein 2; Ppapdc2; Presqualene diphosphate phosphatase; PSDP; RP11-6J24.2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 403313, 619549, 74411
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q66H88, Q8IY26, Q9D4F2
• Gene Symbols: PLPP6
• Immunogen: A 13 amino acid peptide from near the carboxy terminus human PPAPDC2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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