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Invitrogen™ PPAPDC2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA520865
Description
A suggested positive control is Raji cell lysate. PA5-20865 can be used with blocking peptide PEP-0979.
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
Specifications
PPAPDC2 | |
Polyclonal | |
Unconjugated | |
PLPP6 | |
4932443D16Rik; bA6J24.6; FLJ46512; FLJ90191; MGC15483; PDP1; phosphatidic acid phosphatase type 2 domain containing 2; phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; PLPP6; polyisoprenoid diphosphate phosphatase type 1; PPAP2 domain-containing protein 2; Ppapdc2; Presqualene diphosphate phosphatase; PSDP; RP11-6J24.2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
403313, 619549, 74411 | |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
Q66H88, Q8IY26, Q9D4F2 | |
PLPP6 | |
A 13 amino acid peptide from near the carboxy terminus human PPAPDC2. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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