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Invitrogen™ PPAPDC2 Polyclonal Antibody
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Catalog No. PIPA553722
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100 μL
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PIPA553722 100 μL
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Catalog No. PIPA553722 Supplier Invitrogen™ Supplier No. PA553722
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PAHNQMDMFV TLSVDKYSFP SGHATRAALM SR Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 94%.

PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPAPDC2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PLPP6
Gene Accession No. Q8IY26
Gene Alias 4932443D16Rik; bA6J24.6; FLJ46512; FLJ90191; MGC15483; PDP1; phosphatidic acid phosphatase type 2 domain containing 2; phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; PLPP6; polyisoprenoid diphosphate phosphatase type 1; PPAP2 domain-containing protein 2; Ppapdc2; Presqualene diphosphate phosphatase; PSDP; RP11-6J24.2
Gene Symbols PLPP6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PPAPDC2. Recombinant protein control fragment (Product #RP-91123).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 403313
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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