PPARA Mouse anti-Human, Monkey, Clone:5D10C3, Abnova™

Mouse monoclonal antibody raised against recombinant human PPARA.

Supplier:  Abnova Corporation MAB17128

Catalog No. 89-333-491

Description

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq]

Specifications

• Antigen: PPARA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry
  Immunocytochemistry
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Gene: PPARA
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 5D10C3
• Description: peroxisome proliferator-activated receptor alpha
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: MGC2237, MGC2452, NR1C1, PPAR, hPPAR
• Immunogen: Recombinant protein corresponding to amino acid 1-120 of human PPARA from E. coli.
• Gene ID (Entrez): 5465
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid