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Invitrogen™ PPARGC1B Polyclonal Antibody
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Catalog No. PIPA585594
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100 μL
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PIPA585594 100 μL
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Catalog No. PIPA585594 Supplier Invitrogen™ Supplier No. PA585594
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (82%), Rat (83%). Positive Control: rat heart. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPARGC1B
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Ppargc1b
Gene Accession No. Q811R2, Q86YN6
Gene Alias 4631412G21Rik; ERR ligand 1; ERRL1; Perc; peroxisome proliferative activated receptor gamma coactivator 1 beta; peroxisome proliferative activated receptor, gamma, coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma coactivator 1beta-2a; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; PGC1; pgc-1 beta; PGC-1(beta); Pgc1b; PGC1beta; PGC-1beta; PGC-1-beta; PGC-1beta/ERRL1; PGC-1-related estrogen receptor alpha coactivator; PPAR gamma coactivator-1beta protein; PPARG coactivator 1 beta; PPARgamma coactivator 1 beta; PPAR-gamma coactivator 1-beta; PPARGC1; PPARGC1B; PPARGC-1-beta
Gene Symbols Ppargc1b
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PGC1 beta. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133522, 291567
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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