Invitrogen™ PPARGC1B Recombinant Rabbit Monoclonal Antibody (3K4V1)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538114

Catalog No. PIMA538114

Description

Positive Samples: HeLa, SH-SY5Y, Rat testis Immunogen sequence: VFGEIEECEV LTRNRRGEKY GFITYRCSEH AALSLTKGAA LRKRNEPSFQ LSYGGLRHFC WPRYTDYDSN SEEALPASGK SKYEAMDFDS LLKEAQQSLH.

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.

Specifications

• Antigen: PPARGC1B
• Classification: Recombinant Monoclonal
• Concentration: 0.48 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q811R2, Q86YN6
• Gene Symbols: Ppargc1b
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 924-1023 of human PGC1 beta (NP_5735703).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 3K4V1
• Conjugate: Unconjugated
• Gene: Ppargc1b
• Gene Alias: 4631412G21Rik; ERR ligand 1; ERRL1; Perc; peroxisome proliferative activated receptor gamma coactivator 1 beta; peroxisome proliferative activated receptor, gamma, coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma coactivator 1beta-2a; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; PGC1; pgc-1 beta; PGC-1(beta); Pgc1b; PGC1beta; PGC-1beta; PGC-1-beta; PGC-1beta/ERRL1; PGC-1-related estrogen receptor alpha coactivator; PPAR gamma coactivator-1beta protein; PPARG coactivator 1 beta; PPARgamma coactivator 1 beta; PPAR-gamma coactivator 1-beta; PPARGC1; PPARGC1B; PPARGC-1-beta
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 133522, 291567
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid