Invitrogen™ PPFIBP1 Polyclonal Antibody

Catalog No.	Quantity
PIPA551663	100 μL

Catalog No. PIPA551663 Supplier Invitrogen™ Supplier No. PA551663

Description

Rabbit Polyclonal Antibody

Immunogen sequence: DAQGFSDLEK SPSPTPVMGS PSCDPFNTSV PEEFHTTILQ VSIPSLLPAT VSMETSEKSK LTPKPETSFE ENDGNIILGA TVDTQLCDKL LTSSLQKSSS LGNLKKETSD GEKETIQKTS EDRA Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 67%.

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

• Antigen: PPFIBP1
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: PPFIBP1
• Gene Accession No.: Q86W92
• Gene Alias: 4632409B19Rik; AW214454; AW261454; hSGT2; hSgt2p; KIAA1230; L2; liprin beta 1; liprin related protein; liprin-beta 1; liprin-beta-1; PPFIA binding protein 1; Ppfibp1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; protein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2
• Gene Symbols: PPFIBP1
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human PPFIBP1. Recombinant protein control fragment (Product #RP-102023).
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8496
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG