Invitrogen™ PPFIBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144999

Catalog No. FEPA5144999

Description

Immunogen sequence: EEYVCPMELG QASGSASKKG FKPGLDMRLY EEDDLDRLEQ MEDSEGTVRQ IGAFSEGINN LTHMLKEDDM FKDFAARSPS ASITDEDSN Antigen sequence identity: Mouse 97%; Rat 97%.

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

• Antigen: PPFIBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPFIBP1
• Gene Alias: 4632409B19Rik; AW214454; AW261454; hSGT2; hSgt2p; KIAA1230; L2; liprin beta 1; liprin related protein; liprin-beta 1; liprin-beta-1; PPFIA binding protein 1; Ppfibp1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; protein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8496
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86W92
• Gene Symbols: PPFIBP1
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 922-1010. Recombinant protein control fragment (Product #RP-109807).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid