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Invitrogen™ PPFIBP2 Polyclonal Antibody
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Catalog No. PIPA522222
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100 μL
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Catalog No. Quantity
PIPA522222 100 μL
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Catalog No. PIPA522222 Supplier Invitrogen™ Supplier No. PA522222
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431. Predicted reactivity: Mouse (88%), Rat (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The PPFIBP2 (PPFIA Binding Protein 2) gene encodes a protein that belongs to the liprin family, which is involved in intracellular signaling and cytoskeletal organization. Located on chromosome 1, PPFIBP2 is primarily known for its role in synaptic function and cell adhesion. The protein interacts with receptor protein tyrosine phosphatases, particularly PTPRF and PTPRD, and plays a critical role in the formation and maintenance of synaptic contacts. PPFIBP2 facilitates the proper localization of synaptic vesicles and synapse-specific proteins, contributing to synaptic stability and plasticity. Disruption of PPFIBP2 expression or function has been linked to neurological disorders, emphasizing its importance in neural communication. Additionally, PPFIBP2 has been implicated in cancer, where it may influence tumor cell adhesion and migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPFIBP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.79 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene PPFIBP2
Gene Accession No. Q8ND30
Gene Alias Cclp1; coiled-coil-like protein 1; liprin beta 2; liprin-beta-2; PPFIA binding protein 2; Ppfibp2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2; PTPRF interacting protein, binding protein 2 (liprin beta 2); PTPRF-interacting protein-binding protein 2
Gene Symbols PPFIBP2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PPFIBP2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8495
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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