Invitrogen™ PPIG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587435

Catalog No. PIPA587435

Description

Immunogen sequence: MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF; Positive Samples: Jurkat, HepG2, HeLa; Cellular Location: Nucleus matrix, Nucleus speckle.

Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregation defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.

Specifications

• Antigen: PPIG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPIG
• Gene Alias: AU019516; AU022200; B230312B02Rik; CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; CYP; Matrin cyclophilin; matrin cyclophilin (matrin-cyp); matrin-cyp; MGC133241; OTTHUMP00000204761; OTTHUMP00000204762; Peptidyl-prolyl cis-trans isomerase G; peptidylprolyl isomerase G; peptidyl-prolyl isomerase G; peptidylprolyl isomerase G (cyclophilin G); peptidyl-prolyl isomerase G (cyclophilin G); PPIase G; PPIG; Rotamase G; SCAF10; SR-cyclophilin; SRCyp; SR-cyp; SR-related CTD-associated factor 10
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9360
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.41 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q13427
• Gene Symbols: PPIG
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PPIG (NP_0047832).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG