Invitrogen™ PPIG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA517016

Catalog No. PIPA517016

Description

It is not recommended to aliquot this antibody.

Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregation defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.

Specifications

• Antigen: PPIG
• Classification: Polyclonal
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: A2AR02, O55035, Q13427
• Gene Symbols: PPIG
• Immunogen: Synthetic peptide corresponding to residues surrounding Glu391 of human PPIG.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: PPIG
• Gene Alias: AU019516; AU022200; B230312B02Rik; CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; CYP; Matrin cyclophilin; matrin cyclophilin (matrin-cyp); matrin-cyp; MGC133241; OTTHUMP00000204761; OTTHUMP00000204762; Peptidyl-prolyl cis-trans isomerase G; peptidylprolyl isomerase G; peptidyl-prolyl isomerase G; peptidylprolyl isomerase G (cyclophilin G); peptidyl-prolyl isomerase G (cyclophilin G); PPIase G; PPIG; Rotamase G; SCAF10; SR-cyclophilin; SRCyp; SR-cyp; SR-related CTD-associated factor 10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 228005, 83624, 9360
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov