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Invitrogen™ Periplakin Polyclonal Antibody
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Catalog No. PIPA542095
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100 μL
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Catalog No. Quantity
PIPA542095 100 μL
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Catalog No. PIPA542095 Supplier Invitrogen™ Supplier No. PA542095
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Description

Rabbit Polyclonal Antibody

Peptide sequence: EKSRAQEKVT EKEVVKLQND PQLEAEYQQL QEDHQRQDQL REKQEEELSF Sequence homology: Human: 100%; Pig: 82%.

The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Periplakin
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Ppl
Gene Accession No. O60437
Gene Alias 190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; 195kDa protein; AW553870; KIAA0568; MGC134872; Periplakin; Ppl
Gene Symbols Ppl
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human PPL.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5493
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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