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Invitrogen™ Periplakin Polyclonal Antibody
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Catalog No. PIPA560020
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100 μL
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PIPA560020 100 μL
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Catalog No. PIPA560020 Supplier Invitrogen™ Supplier No. PA560020
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LLAGLDKVAS DLDRQEKAIT GILRPPLEQG RAVQDSAERA KDLKNITNEL LRIEPEKTRS TAEGEAFIQA LPGSGTTPLL RTRVEDTNRK YEHLL Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.

The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Periplakin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ppl
Gene Accession No. O60437
Gene Alias 190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; 195kDa protein; AW553870; KIAA0568; MGC134872; Periplakin; Ppl
Gene Symbols Ppl
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PPL. Recombinant protein control fragment (Product #RP-98660).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5493
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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