Invitrogen™ PPM1A Monoclonal Antibody (7F12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517154

Catalog No. PIMA517154

Description

MA5-17154 targets PPM1A in FACS, indirect ELISA, and WB applications and shows reactivity with Human and Non-human primate samples. The MA5-17154 immunogen is purified recombinant fragment of human PPM1A (amino acids: 202-382) expressed in E. Coli. MA5-17154 detects PPM1A which has a predicted molecular weight of approximately 42.4kDa.

PPM1A (Protein phosphatase 1A) is also named as PPPM1A and belongs to the PP2C family. It is a serine/threonine protein phosphatase that is essential for regulating cellular stress responses in eukaryotes. PPM1A plays an important role in tumor suppression and that it negatively controls many signaling pathways which are critical for trophoblast invasion. This protein distributes in both the cytoplasm and nucleus of mammalian cells. It has 2 isoforms produced by alternative splicing.

Specifications

• Antigen: PPM1A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P20650, P35813, P49443
• Gene Symbols: PPM1A
• Immunogen: Purified recombinant fragment of human PPM1A (amino acids: 202-382) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 7F12
• Conjugate: Unconjugated
• Gene: PPM1A
• Gene Alias: 2310003C21Rik; 2900017D14Rik; AI427932; AU017636; IA; MMPa-2; Mpp alpha; MPPa-1; Pp2c1; PP2CA; PP2Calpha; PP2C-alpha; PPM1A; PPPM1A; Protein phosphatase 1A; protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform; protein phosphatase 1A, magnesium dependent, alpha isoform; protein phosphatase 2C isoform alpha; Protein phosphatase IA; Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform; Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform; protein phosphatase, Mg2+/Mn2+ dependent 1A; protein phosphatase, Mg2+/Mn2+ dependent, 1A
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 19042, 24666, 5494
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid