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Invitrogen™ PPM1F Polyclonal Antibody
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Catalog No. PIPA515571
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400 μL
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PIPA515571 400 μL
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Catalog No. PIPA515571 Supplier Invitrogen™ Supplier No. PA515571
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Description

Rabbit Polyclonal Antibody

PPM1F Polyclonal Antibody for Western Blot, IHC (P)

PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPM1F
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PPM1F
Gene Accession No. P49593, Q8CGA0
Gene Alias 1110021B16Rik; 4933427B07Rik; Ca(2+)/calmodulin-dependent protein kinase phosphatase; calcium/calmodulin-dependent protein kinase phosphatase; caM-kinase phosphatase; CAMKP; CaMKPase; FEM-2; hFem-2; KIAA0015; mKIAA0015; Partner of PIX 2; partner of PIX2; POPX2; PP2C phosphatase; Ppm1f; Protein fem-2 homolog; protein phosphatase 1F; protein phosphatase 1F (PP2C domain containing); protein phosphatase, Mg2+/Mn2+ dependent 1F; protein phosphatase, Mg2+/Mn2+ dependent, 1F
Gene Symbols PPM1F
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human PPM1F.
Purification Method Size-exclusion - Dialysis, Ammonium sulfate precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 68606, 9647
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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