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PPM1F Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987856
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50-198-7856 100 μL
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Catalog No. 50-198-7856 Supplier Bioss Supplier No. BS7595R
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Description

Rabbit Polyclonal Antibody

PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.

Specifications

Antigen PPM1F
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PPM1F
Gene Accession No. P49593
Gene Alias 1110021B16Rik; 4933427B07Rik; Ca(2+)/calmodulin-dependent protein kinase phosphatase; calcium/calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; CAMKP; CaMKPase; FEM-2; hFem-2; KIAA0015; mKIAA0015; Partner of PIX 2; partner of PIX2; POPX2; PP2C phosphatase; Ppm1f; Protein fem-2 homolog; Protein phosphatase 1F; protein phosphatase 1F (PP2C domain containing); protein phosphatase, Mg2+/Mn2+ dependent 1F; protein phosphatase, Mg2+/Mn2+ dependent, 1F
Gene Symbols PPM1F
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PPM1F.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9647
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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