PPP1CA Monoclonal Antibody (OTI6E5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA808819

Catalog No. 50-168-2393

Description

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PPP1CA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P62136
• Gene Symbols: PPP1CA
• Immunogen: Full length human recombit protein of human PPP1CA produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6E5
• Conjugate: Unconjugated
• Gene: PPP1CA
• Gene Alias: PP-1A, PP1A, PP1alpha, PPP1A
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5499
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid