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PPP1CA Mouse anti-Human, Clone:1C11-C10-H5-E9, Abnova™

Catalog No. 89333881 Shop All Abnova Corporation Products
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89-333-881 100 μg
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Catalog No. 89-333-881 Supplier Abnova Corporation Supplier No. MAB17659

Description

Mouse monoclonal antibody raised against recombinant human PPP1CA.

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen PPP1CA
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1C11-C10-H5-E9
Conjugate Unconjugated
Description protein phosphatase 1, catalytic subunit, alpha isoform
Dilution Immunocytochemistry (1:300)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
Formulation In buffer containing 0.1M Tris-Glycine, 150 mM NaCl, pH 7.4 (50% glycerol, 0.2% sodium azide)
Gene PPP1CA
Gene Alias MGC15877, MGC1674, PP-1A, PPP1A
Host Species Mouse
Immunogen Recombinant protein corresponding to a fragment of human PPP1CA from E. coli.
Quantity 100 μg
Gene ID (Entrez) 5499
Test Specificity This antibody detects endogenous levels of PPP1A and does not cross-react with related proteins.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG1
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