Invitrogen™ PPP1R12B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555001

Catalog No. PIPA555001

Description

Immunogen sequence: GTGINFWTKD EDETDGSEEV KETWHERLSR LESGGSNPTT SDSYGDRASA RARREAREAR LATLTSRVEE DSNRDYKKLY ESALTENQKL KTKLQEAQLE LADIKS Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.

Specifications

• Antigen: PPP1R12B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP1R12B
• Gene Alias: 1810037O03Rik; 9530009M10Rik; AI132431; Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 2; MYPT2; PP1bp55; PPP1R12B; Protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4660
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60237
• Gene Symbols: PPP1R12B
• Immunogen: Recombinant protein corresponding to Human PPP1R12B. Recombinant protein control fragment (Product #RP-94025).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG