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Invitrogen™ PPP1R12B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555001

Catalog No. PIPA555001


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Description

Description

Immunogen sequence: GTGINFWTKD EDETDGSEEV KETWHERLSR LESGGSNPTT SDSYGDRASA RARREAREAR LATLTSRVEE DSNRDYKKLY ESALTENQKL KTKLQEAQLE LADIKS Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PPP1R12B
Polyclonal
Unconjugated
PPP1R12B
1810037O03Rik; 9530009M10Rik; AI132431; Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 2; MYPT2; PP1bp55; PPP1R12B; Protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12B
Rabbit
Antigen affinity chromatography
RUO
4660
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.4 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
O60237
PPP1R12B
Recombinant protein corresponding to Human PPP1R12B. Recombinant protein control fragment (Product #RP-94025).
100 μL
Primary
Human
Antibody
IgG
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