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Invitrogen™ PPP1R12B Polyclonal Antibody
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Catalog No. PIPA555135
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100 μL
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PIPA555135 100 μL
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Catalog No. PIPA555135 Supplier Invitrogen™ Supplier No. PA555135
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TQGVTLTDLQ EAERTFSRSR AERQAQEQPR EKPTDTEGLE GSPEKHEPSA VPATEAGEGQ QPWGRSLDEE PICHRLRCPA QPDKPTTPAS PSTSRPSLYT SSHLLW Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 79%.

Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP1R12B
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PPP1R12B
Gene Accession No. O60237
Gene Alias 1810037O03Rik; 9530009M10Rik; AI132431; Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; myosin phosphatase-targeting subunit 2; MYPT2; PP1bp55; PPP1R12B; Protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12B
Gene Symbols PPP1R12B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PPP1R12B. Recombinant protein control fragment (Product #RP-94024).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4660
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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