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Invitrogen™ PPP1R3B Polyclonal Antibody
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Catalog No. PIPA555965
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100 μL
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PIPA555965 100 μL
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Catalog No. PIPA555965 Supplier Invitrogen™ Supplier No. PA555965
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DRDTFSFDIS LPEKIQSYER MEFAVYYECN GQTYWDSNRG KNYRIIRAEL KSTQGMTKPH SGPDLGISFD QFGSPRCSYG LF Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 88%.

Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP1R3B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PPP1R3B
Gene Accession No. Q86XI6
Gene Alias 33 kDa glycogen-binding protein; 6430576E21; AW821953; GL; Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL; hepatic glycogen-targeting subunit, G(L); PP1 subunit R4; PPP1R3B; PPP1R4; protein phosphatase 1 (GL-subunit); protein phosphatase 1 regulatory subunit 3B; Protein phosphatase 1 regulatory subunit 4; protein phosphatase 1 subunit GL; protein phosphatase 1, regulatory (inhibitor) subunit 3B; protein phosphatase 1, regulatory subunit 3B; PTG; R4
Gene Symbols PPP1R3B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PPP1R3B. Recombinant protein control fragment (Product #RP-93907).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79660
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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