Invitrogen™ PPP1R7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544565

Catalog No. PIPA544565

Description

Peptide sequence: QNLIKCIENL EELQSLRELD LYDNQIKKIE NLEALTELEI LDISFNLLRN Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.

Specifications

• Antigen: PPP1R7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP1R7
• Gene Alias: 2310014J01Rik; hypothetical protein LOC560323; im:7136431; Ppp1r7; Protein phosphatase 1 regulatory subunit 22; protein phosphatase 1 regulatory subunit 7; protein phosphatase 1, regulatory (inhibitor) subunit 7; protein phosphatase 1, regulatory subunit 7; protein phosphatase-1 regulatory subunit 7; Sds22; testis secretory sperm-binding protein Li 210a; zgc:123325
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5510
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q15435
• Gene Symbols: PPP1R7
• Immunogen: Synthetic peptide directed towards the middle region of human PPP1R7.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG