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Invitrogen™ PPP1R7 Polyclonal Antibody
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Catalog No. PIPA556956
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PIPA556956 100 μL
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Catalog No. PIPA556956 Supplier Invitrogen™ Supplier No. PA556956
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LENNNKLTML DIASNRIKKI ENISHLTELQ EFWMNDNLLE SWSDLDELKG ARSLETVYLE RNPLQKDPQY RRKVMLALPS VRQIDATF Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP1R7
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PPP1R7
Gene Accession No. Q15435
Gene Alias 2310014J01Rik; hypothetical protein LOC560323; im:7136431; Ppp1r7; Protein phosphatase 1 regulatory subunit 22; protein phosphatase 1 regulatory subunit 7; protein phosphatase 1, regulatory (inhibitor) subunit 7; protein phosphatase 1, regulatory subunit 7; protein phosphatase-1 regulatory subunit 7; Sds22; testis secretory sperm-binding protein Li 210a; zgc:123325
Gene Symbols PPP1R7
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PPP1R7. Recombinant protein control fragment (Product #RP-102621).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5510
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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