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Invitrogen™ PPP1R7 Polyclonal Antibody
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Catalog No. PIPA588935
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100 μL
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PIPA588935 100 μL
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Catalog No. PIPA588935 Supplier Invitrogen™ Supplier No. PA588935
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IASNRIKKIE NISHLTELQE FWMNDNLLES WSDLDELKGA RSLETVYLER NPLQKDPQYR RKVMLALPSV RQIDATFVRF; Positive Samples: Mouse liver, Mouse kidney, Rat liver; Cellular Location: Nucleus.

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP1R7
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.89 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PPP1R7
Gene Accession No. Q3UM45, Q5HZV9
Gene Alias 2310014J01Rik; hypothetical protein LOC560323; im:7136431; Ppp1r7; Protein phosphatase 1 regulatory subunit 22; protein phosphatase 1 regulatory subunit 7; protein phosphatase 1, regulatory (inhibitor) subunit 7; protein phosphatase 1, regulatory subunit 7; protein phosphatase-1 regulatory subunit 7; Sds22; testis secretory sperm-binding protein Li 210a; zgc:123325
Gene Symbols PPP1R7
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 281-360 of human PPP1R7 (NP_0027031).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 301618, 66385
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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